- Free worldwide shipping, tracked and insured
- Same day dispatch, customs handled
- Certificate of analysis for every batch
- Cellular antioxidant and redox research
- Oxidative-stress pathway studies
- GSH/GSSG redox-couple research
Overview
What is Glutathione?
Glutathione (GSH) is a tripeptide of glutamate, cysteine, and glycine, used as a research compound in studies of cellular antioxidant activity, redox homeostasis, and detoxification. Supplied for in-vitro and laboratory research use only.
Mechanism in research
How Glutathione is studied
In published research reduced glutathione (GSH) was described as an essential non-enzymatic cellular antioxidant, central to redox homeostasis through the GSH/GSSG couple, detoxification reactions, and redox signaling. These pathways are investigated in models of oxidative stress; corresponding mechanisms in humans are studied in ongoing redox-biology research.
Reported targets & pathways
- GSH/GSSG redox couple
- Glutathione peroxidase and reductase pathways
- Cellular detoxification (conjugation) pathways
- Redox signaling
Research applications
Where Glutathione is used in research
Areas of study described in the published literature. Listed for research reference only.
Oxidative stress
Used in research on cellular antioxidant capacity and oxidative-stress models.
Redox biology
Studied as the central component of the GSH/GSSG redox couple.
Detoxification
Applied to investigate conjugation and detoxification pathways.
Redox signaling
Explored in research on redox-dependent cell signaling.
Reference data
Glutathione specifications
- Composition
- Tripeptide (gamma-Glu-Cys-Gly)
- Classification
- Non-enzymatic cellular antioxidant
- Appearance
- White lyophilized powder
- Solubility
- Soluble in water and buffer
- Molecular formula
- C10H17N3O6S
- Molecular weight
- 307.32 g/mol
- Purity
- 99.69%
- CAS number
- 70-18-8
- PubChem CID
- 124886
Selected research
Published studies on Glutathione
Peer-reviewed references for further reading. Findings describe in-vitro and animal research; mechanisms and outcomes in humans are not established.
Vitamins and Hormones · 2023
Reviewed reduced glutathione (GSH) as an essential non-enzymatic cellular antioxidant, describing its role in redox homeostasis, the GSH/GSSG couple, detoxification, and redox signaling.
Biochimica et Biophysica Acta · 2013
Reviewed the two-step cytosolic biosynthesis of glutathione by glutamate cysteine ligase and GSH synthetase, and described how this pathway was reported to be tightly regulated and dysregulated in disease states.
Antioxidants & Redox Signaling · 2005
Reviewed how shifts in the intracellular GSH/GSSG ratio were reported to influence redox-sensitive signaling pathways and cysteine-based redox chemistry in the context of lung inflammation.
Quality
Independently verified, batch by batch
Tested every batch
Every batch of Glutathione is independently analyzed by a third-party laboratory before it is released.
Independently verified
Identity and purity are confirmed by an independent third-party laboratory. This batch is verified to 99.69% purity.
Certificate of analysis
Every batch is independently tested with a certificate of analysis. A digital COA is available on request.
Reviews
What researchers say about Glutathione
snabbt till stockholm
snabbare till stockholm än jag trodde, typ sex dagar. förpackningen höll, allt helt
consistent readings
ran it beside our reference and the readings were consistent batch to batch. dissolves clean in buffer. nothing to flag from warsaw.
good run to brisbane
Decent time to brisbane considering the distance. Vials sealed clean, assay matched, will reorder
happy with this one
First order and it was in Madrid inside a week. Vials all sealed and mixes clear. No drama
even the paperwork
Fourth lot of glutathione for us and it is the same as always, mixes clear, readings sat where the old lots sat. What surprised me was the invoice. I asked them to redo it with our VAT number for the accounts people and it came back inside the hour, with our other suppliers that is three emails minimum.
still reduced on arrival
glutathione is the one im always wary about, how much of it oxidises before it gets to us. gsh/gssg was fine when it landed in aarhus. bit paranoid of me maybe, its never come back bad yet
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