- Free worldwide shipping, tracked and insured
- Same day dispatch, customs handled
- Certificate of analysis for every batch
- Cellular antioxidant and redox research
- Oxidative-stress pathway studies
- GSH/GSSG redox-couple research
Overview
What is Glutathione?
Glutathione (GSH) is a tripeptide of glutamate, cysteine, and glycine, used as a research compound in studies of cellular antioxidant activity, redox homeostasis, and detoxification. Supplied for in-vitro and laboratory research use only.
Mechanism in research
How Glutathione is studied
In published research reduced glutathione (GSH) was described as an essential non-enzymatic cellular antioxidant, central to redox homeostasis through the GSH/GSSG couple, detoxification reactions, and redox signaling. These pathways are investigated in models of oxidative stress; corresponding mechanisms in humans are studied in ongoing redox-biology research.
Reported targets & pathways
- GSH/GSSG redox couple
- Glutathione peroxidase and reductase pathways
- Cellular detoxification (conjugation) pathways
- Redox signaling
Research applications
Where Glutathione is used in research
Areas of study described in the published literature. Listed for research reference only.
Oxidative stress
Used in research on cellular antioxidant capacity and oxidative-stress models.
Redox biology
Studied as the central component of the GSH/GSSG redox couple.
Detoxification
Applied to investigate conjugation and detoxification pathways.
Redox signaling
Explored in research on redox-dependent cell signaling.
Reference data
Glutathione specifications
- Composition
- Tripeptide (gamma-Glu-Cys-Gly)
- Classification
- Non-enzymatic cellular antioxidant
- Molecular formula
- C10H17N3O6S
- Molecular weight
- ~307.32 g/mol (PubChem CID 124886)
- Appearance
- White lyophilized powder
- Solubility
- Soluble in water and buffer
- Molecular formula
- C10H17N3O6S
- Molecular weight
- 307.32 g/mol
- Purity
- 99.69%
- CAS number
- 70-18-8
- PubChem CID
- 124886
Selected research
Published studies on Glutathione
Peer-reviewed references for further reading. Findings describe in-vitro and animal research; mechanisms and outcomes in humans are not established.
Vitamins and Hormones · 2023
Reviewed reduced glutathione (GSH) as an essential non-enzymatic cellular antioxidant, describing its role in redox homeostasis, the GSH/GSSG couple, detoxification, and redox signaling.
Biochimica et Biophysica Acta · 2013
Reviewed the two-step cytosolic biosynthesis of glutathione by glutamate cysteine ligase and GSH synthetase, and described how this pathway was reported to be tightly regulated and dysregulated in disease states.
Antioxidants & Redox Signaling · 2005
Reviewed how shifts in the intracellular GSH/GSSG ratio were reported to influence redox-sensitive signaling pathways and cysteine-based redox chemistry in the context of lung inflammation.
Quality
Independently verified, batch by batch
Tested every batch
Every batch of Glutathione is independently analyzed by a third-party laboratory before it is released.
Independently verified
Identity and purity are confirmed by an independent third-party laboratory. This batch is verified to 99.69% purity.
Certificate of analysis
Every batch is independently tested with a certificate of analysis. We send a digital COA with your order.
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